Can AI Look at Your Retina and Diagnose Alzheimer's? The author of believes AI could bring big changes to the world of medicine. For decades now, it's been fairly well established that once you turn 40 you should start paying more attention to your body. That's when women are supposed to start getting mammograms and men are supposed to start paying a bit more attention to their prostates. Over the next decade, you'll start getting colonoscopies, and from then on out, it feels like a gradual march of doctor's appointments and tests until your body collapses sometime in your seventies or eighties.

Anthropic's Daniela Amodei Believes the Market Will Reward Safe AI The Trump administration might think regulation is killing the AI industry, but Anthropic president Daniela Amodei disagrees. The Trump administration may think regulation is crippling the AI industry, but one of the industry's biggest players doesn't agree. At WIRED's Big Interview event on Thursday, Anthropic president and cofounder Daniela Amodei told WIRED editor at large Steven Levy that even though Trump's AI and crypto czar, David Sacks, may have tweeted that her company is "running a sophisticated regulatory capture strategy based on fear-mongering," she's convinced her company's commitment to calling out the potential dangers of AI is making the industry stronger. WIRED's iconic series returned to San Francisco with a series of unforgettable, in-depth live conversations. Check out more highlights here .

Lisa Su leads Nvidia's biggest rival in the AI chip market. When asked at WIRED's Big Interview event if AI is a bubble, the company's CEO said "Emphatically, from my perspective, no." Earlier this year, WIRED said that AMD CEO Lisa Su was " out for Nvidia's blood ." The American chipmaker is still small compared to the juggernaut that is Nvidia--their market caps are $353 billion and $4.4 trillion, respectively--but Su's company is gaining steam. Today, when Su took the stage at WIRED's Big Interview conference in San Francisco, she had something else in her sights: the AI bubble .

Practicing good "operations security" is essential to staying safe online. Here's a complete guide for teenagers (and anyone else) who wants to button up their digital lives. Teenagers have always been formidable hackers. In fact, in recent years, some of the most high-profile and brazen digital attacks around the world have been carried out by teens. And whether you've never given much thought to your digital privacy and security or you've started to rein in your data, you can use this guide to implement basic precautions and keep operations security in mind. In other words, this guide contains advice and ideas to help you conceptualize how people can find out information about you from your digital activities--and start to minimize what's out there in ways you didn't intend. Some people are more private by nature, and others prioritize putting themselves out there. But even if you're a 24/7 streamer, you can still think about your operations security, commonly known as opsec. What can viewers see in your room while you're streaming?

From robot vacuums to Dyson stick vacs, don't miss these Black Friday deals happening on our favorite vacuums in every category. There's a lot of shopping you can do this weekend, but these Black Friday vacuum cleaner deals are ones you shouldn't skip if you need any kind of cleaning upgrade. Changing to a stick vacuum hugely improved my life after moving to a three-story home, but all kinds of vacuum types can turn your life around. Never have time to vacuum or mop? You'll want a handheld vacuum.

At New Zealand's Kawaiican cybersecurity convention, organizers hacked together a way for attendees to track CO levels throughout the venue--even before they arrived. Hacker conferences--like all conventions--are notorious for giving attendees a parting gift of mystery illness. To combat "con crud," New Zealand's premier hacker conference, Kawaiicon, quietly launched a real-time, room-by-room carbon dioxide monitoring system for attendees. To get the system up and running, event organizers installed DIY CO monitors throughout the Michael Fowler Centre venue before conference doors opened on November 6. Attendees were able to check a public online dashboard for clean air readings for session rooms, kids' areas, the front desk, and more, all before even showing up. It's ALMOST like we are all nerds in a risk-based industry, the organizers wrote on the convention's website.

In a closed-door workshop led by Anthropic and Stanford, leading AI startups and researchers discussed guidelines for chatbot companions, especially for younger users. At Stanford for eight hours on Monday, representatives from Anthropic, Apple, Google, OpenAI, Meta, and Microsoft met in a closed-door workshop to discuss the use of chatbots as companions or in roleplay scenarios. Interactions with AI tools are often mundane, but they can also lead to dire outcomes. Users sometimes experience mental breakdowns during lengthy conversations with chatbots or confide in them about their suicidal ideations . "We need to have really big conversations across society about what role we want AI to play in our future as humans who are interacting with each other," says Ryn Linthicum, head of user well-being policy at Anthropic .

As OpenAI expands in every direction, the new CEO of Applications is on a mission to make ChatGPT indispensable and lucrative. In case OpenAI's structure couldn't get any weirder--a nonprofit in charge of a for-profit that's become a public benefit corporation--it now has two CEOs. There's Sam Altman, chief executive of the whole company, who manages research and compute. And as of this summer, there's Fidji Simo, the former CEO of Instacart, who manages everything else. Simo hasn't been seen much at OpenAI's San Francisco office since she began as CEO of Applications in August. But her presence is felt at every level of the company--not least because she's heading up ChatGPT and basically every function that might make OpenAI money. Simo is dealing with a relapse of postural orthostatic tachycardia syndrome (POTS) that makes her prone to fainting if she stands for long periods of time. "Being present from 8 am to midnight every day, responding within five minutes, people feel like I'm there and that they can reach me immediately, that I jump on the phone within five minutes," she tells me. Employees confirm that this is true. OpenAI's famously Slack-driven culture can be overwhelming for new hires. Employees say she is often seen popping into channels and threads, sharing thoughts and asking questions.

OpenAI has committed to buying billions of dollars worth of compute from AWS--the latest in a string of major deals brokered by the AI startup. OpenAI has signed a multi-year deal with Amazon to buy $38 billion worth of AWS cloud infrastructure to train its models and serve its users. The deal is yet another sign of the AI industry becoming increasingly entangled, with OpenAI now at the center of major partnerships with industry players including Google, Oracle, Nvidia, and AMD. The AWS agreement is also notable because OpenAI rose to prominence in part through its partnership with Microsoft--Amazon's biggest cloud rival. Amazon is also a major backer of one of OpenAI's key competitors, Anthropic.

Your Friend Asked You a Question. Your friend came to you because they respect your knowledge and opinion, and outsourcing the answer to a machine is lazy and rude. Back in the 2010s, a website called Let Me Google That For You gained a notable amount of popularity for serving a single purpose: snark. The site lets you generate a custom link that you can send somebody who asks you a question. When they click the link, it plays an animation of the process of typing a question into Google.